RESULTS

  • 10 symposium a year
  • 20 million dollars in research funding a year
  • 100 publication a year
─ Aging and Biology Research ─
  • Cheng YH, Lin FH, Wang CY, Hsiao CY, Chen HC, Kuo HY, Tsai TF, Chiou SH. Recovery of oxidative stress-induced damage in Cisd2-deficient cardiomyocytes by sustained release of ferulic acid from injectable hydrogel. Biomaterials 103: 207-218 (2016) (IF = 8.387).
  • Liu CC, Lin YC, Chen YH, Chen CM, Pang LY, Chen HA, Wu PR, Lin MY, Jiang ST, Tsai TF, Chen RH. Cul3-KLHL20 ubiquitin ligase governs the turnover of ULK1 and VPS34 complexes to control autophagy termination. Molecular Cell 61(1): 84-97 (2016) (IF = 13.958).
  • Wei Cheng, Edmund T. Rolls; Jiang Qiu; Wei Liu, Yanqing Tang, Chu-Chung Huang, XinFa Wang, Jie Zhang, Wei Lin, Lirong Zheng, JunCai Pu, Shih-Jen Tsai, Albert C Yang, Ching-Po Lin*, Fei Wang*, Peng Xie*, Jianfeng Feng* (2016) Medial reward and lateral non-reward orbitofrontal cortex circuits change in opposite directions in depression. Brain (in press)
  • Chih-Ping Chung, Kun-Hsien Chou, Wei-Ta Chen, Li-Kuo Liu, Wei-Ju Lee, Liang-Kung Chen*, Ching-Po Lin, Pei-Ning Wang* (2016) Strictly Lobar Cerebral Microbleeds Are Associated with Deficits in Global Cognitive and Visuospatial Executive Function Cognitive Impairment. Stroke (in press)
  • Kun-Hsien Chou, Fu-Chi Yang, Jong-Ling Fuh, Chen-Yuan Kuo, Yi-Hsin Wang, Jiing-Feng Lirng, Yung-Yang Lin, Shuu-Jiun Wang*, Ching-Po Lin* (2016) Bout-associated intrinsic functional network changes in cluster headache: a longitudinal resting-state functional MRI study. Cephalalgia (in press)
  • Li-Ming Hsu, Xia Liang, Hong Gu, Julia K. Brynildsen, Jennifer A. Stark, Jessica A Ash, Ching-Po Lin, Hanbing Lu, Peter R Rapp, Elliot A. Stein, Yihong Yang (2016) The Constituents and Functional Implications of the Rat Default Mode Network. Proceedings of the National Academy of Sciences (in press)
  • Chiao-Yun Chen, Adrian Raine, Kun-Hsien Chou, I-Yun Chen, Daisy Hung, Ching-Po Lin*(2016) Abnormal White Matter Integrity in Rapists as Indicated by Diffusion Tensor Imaging. BMC Neuroscience (in press)
  • Albert C. Yang, Shih-Jen Tsai, Mu-En Liu, Chu-Chung Huang, Ching-Po Lin* (2016) The association of aging with white matter integrity and functional connectivity hubs. Frontiers in Aging Neurosciences 8(2): 919-13
  • Chu-Chung Huang, Mu-En Liu, Hung-Wen Kao, Kun-Hsien Chou, Albert C. Yang, Ying-Hsiu Wang, Tong-Ru Chen, Shih-Jen Tsai, Ching-Po Lin* (2016) Effect of Alzheimer's Disease Risk Variant rs3824968 at SORL1 on Regional Gray Matter Volume and Age-Related Interaction in Adult Lifespan. Scientific Reports 6(23362): srep23362
  • Chih-Ping Chung, Kun-Hsien Chou, Wei-Ta Chen, Li-Kuo Liu, Wei-Ju Lee, Liang-Kung Chen*, Ching-Po Lin*, Pei-Ning Wang* (2016) Cerebral microbleeds are associated with physical frailty – a community-based study. Neurobiology of Aging (in press)
  • Chun-Jen Lin, Feng-Chi Chang, Kun-Hsien Chou, Pei-Chi Tu, Yi-Hsuan Lee, Ching-Po Lin, Pei-Ning Wang, I-Hui Lee (2016) Intervention versus Aggressive Medical Therapy for Cognition in Severe Asymptomatic Carotid Stenosis. AJNR (in press)
  • Tzu-Hsien Lai, Kung-Hsien Chou, Jong-Ling Fuh, Pei-Lin Lee, Yi-Chia Kung, Ching-Po Lin, Shuu-Jiun Wang (2016) Gray matter changes related to medication overuse in patients with chronic migraine. Cephalalgia (in press)
  • Wang CH, Tsai TF, Wei YH. Role of mitochondrial dysfunction and dysregulation of Ca2+ homeostasis in insulin insensitivity of mammalian cells. Ann N Y Acad Sci. 2015 Jul 27. doi: 10.1111/nyas.12838. [Epub ahead of print] (IF = 4.313).
  • Tsai PH, Chien Y, Chuang JH, Chou SJ, Chien CH, Lai YH, Li HY, Ko YL, Chang YL, Wang CY, Liu YY, Lee HC, Yang CH, Tsai TF, Lee YY, Chiou SH. Dysregulation of Mitochondrial Functions and Osteogenic Differentiation in Cisd2-deficient Murine Induced Pluripotent Stem Cells. Stem Cells Dev. 2015 Jul 31. [Epub ahead of print] (IF= 3.727).
  • Wang SH, Yeh SH, Shiau CW, Chen KF, Lin WH, Tsai TF, Teng YC, Chen DS and Chen PJ. Sorafenib inhibits hepatitis B virus X activated oncogenic androgen pathway in liver through SHP-1. J Natl Cancer Inst. 2015 Jul 23;107(10) (IF = 15.161).
  • Yang CH, Chou HC, Fu YN, Yeh CL, Cheng HW, Chang IC, Liu KJ, Chang GC, Tsai TF, Tsai SF, Liu HP, Wu YC, Chen YT, Huang SF, Chen YR. EGFR over-expression in non-small cell lung cancers harboring EGFR mutations is associated with marked down-regulation of CD82. BBA-Molecular Basis of Disease 1852(7):1540-1549 (2015) (IF = 5.089).
  • Teng CF, Hsieh WC, Yang CW, Su HM, Tsai TF, Sung WC, Huang W, Su IJ. A biphasic response pattern of lipid metabolomics in the stage progression of hepatitis B virus X tumorigenesis. Molecular Carcinogenesis 2015 Jan 15. doi: 10.1002/mc.22266. [Epub ahead of print] (IF = 4.77).
  • Shiue SC, Huang MZ, Tsai TF, Chang A, Choo K, Huang CJ, Su TS. Expression profile and down-regulation of argininosuccinate synthetase in hepatocellular carcinoma in a transgenic mouse model. J Biomed Sci. 2015 Jan 23;22(1):10. (IF = 2.74).
  • Wu KC, Lu YH, Peng YH, Tsai TF, Kao YH, Yang HT, Lin CJ. Decreased expression of organic cation transporters, Oct1 and Oct2, in brain microvessels and its implication to MPTP-induced dopaminergic toxicity in aged mice. J Cereb Blood Flow Metab.35(1):37-47 (2015) (IF = 5.339).
  • Wu KC, Lu YH, Peng YH, Tsai TF, Kao YH, Yang HT, Lin CJ. Decreased expression of organic cation transporters, Oct1 and Oct2, in brain microvessels and its implication to MPTP-induced dopaminergic toxicity in aged mice. J Cereb Blood Flow Metab.35(1):37-47 (2015). [Epub ahead of print, 2014 Sep 24] (IF = 5.339).
  • Wiley SE, Andreyev AY, Karisch R, Perkins G, Wall EA, van der Geer P, Chen YF, Tsai TF, Simon MI, Neel BG, Dixon JE, Murphy AN. Wolfram Syndrome protein, Miner1 (Cisd2), regulates sulfhydryl redox status, the unfolded protein response and Ca2+ homeostasis. EMBO Molecular Medicine 5(6): 904-918 (2013). (IF = 8.245; Miner1, synonym Cisd2)
  • Hsieh WC, Yang CW, Haung YS, Chao TW, Tsai TF, Su IJ. Chemoprevention of HBV-related hepatocellular carcinoma by the combined product of resveratrol and silymarinin transgenic mice. Functional Foods in Health and Disease 3(9): 341-352 (2013).
  • Yang CY, Chen JB, Tsai TF, Tsai YC, Tsai CY, Liang PH, Hsu TL, Wu CY, Netea MG, Wong CH, Hsieh SL. CLEC4F is an inducible C-type lectin in F4/80-positive cells and is involved in alpha-galactosylceramide presentation in liver. PLoS ONE 8(6): e65070 (2013) (IF = 3.534).
  • Hsieh YH, Su IJ, Yen CJ, Tsai TF, Tsai HW, Tsai HN, Huang YJ, Chen YY, Ai YL, Kao LY, Hsieh WC, Wu HC, Huang W. Histone deacetylase inhibitor suberoylanilide hydroxamic acid suppresses the pro-oncogenic effects induced by hepatitis B virus pre-S2 mutant oncoprotein and represents a potential chemopreventive agent in high-risk chronic HBV patients. Carcinogenesis 34(2): 475-485 (2013) (IF = 5.266)
─ Aging and Health Research ─
  • Peng LN, Chen YT, Liu LK, Lin MH, Chen WM, Chen LK (corresponding author). Clinical benefits of post-acute care for older patients with hip fractures in Taiwan: a prospective intervention cohort study. Geriatr Gerontol Int 2016;16:28-36 [SCI]
  • Huang CY, Liu LK, Hwang AC, Chen YC, Peng LN, Lin MH, Chen LK (corresponding author). Association of sarcopenia and cognitive impairment among community-dwelling elderly Taiwanese: the results from I-Lan longitudinal aging study. Rejuvenation Res 2016;19:71-8 [SCI]
  • Lu WH, Chiou ST, Chen LK (co-corresponding author), Hsiao FY. Functional and mental health outcomes of the joint effects of spouse health: the potential threats of “concordant frailty”. J Am Med Dir Assoc 2016;17:324-30.
  • Wu YH, Hwang AC, Liu LK, Peng LN, Chen LK. Sex differences of sarcopenia in Asian populations: the implications in diagnosis and management. J Clin Gerontol Geriatr 2016;7:37-43
  • Chung CP, Chou KH, Chen WT, Liu LK, Lee WJ, Chen LK, Lin CP, Wang PN. Cerebral microbleeds and frailty syndrome: a community-based study. Neurobiol Aging 2016;44:143-50. [SCI]
  • Lu WH, Lee WJ, Chen LK, Hsiao FY. Comparisons of annual healthcare utilization, drug consumption and medical expenditure between the elderly and general population in Taiwan. J Clin Gerontol Geriatr 2016;7:44-47.
  • Hwang AC, Zhan YR, Liu LK, Lee WJ, Peng LN, Lin MH, Chen LK (corresponding author). Higher daily activity is associated with muscle strength after midlife, but not muscle mass after age of 75: results from I-Lan longitudinal aging study. Medicine 2016;95:e3809
  • Lee WJ, Chen LK, Liang CK, Peng LN, Chiou ST, Chou P. Soluble ICAM-1, independent of IL-6, is associated with prevalent frailty in community-dwelling older Taiwanese people. Plos One 2016;11:e0157877 [SCI]
  • Lee WJ, Liu CY, Sun CC, Chen LK (corresponding author). Walking speed, not muscle mass, is associated with urinary incontinence in community-dwelling older Taiwanese. Neurourol Urodynam (in press)
  • Chi MJ, Liang CK, Lee WJ, Peng LN, Chou MY, Chen LK (corresponding author). Association of elderly-onset diabetes mellitus and mortality in Taiwan: a 10-year nationwide population-based study. J Nutr Health Aging (in press) [SCI]
  • Chen LK (corresponding author). Life course approach for healthy aging. Eur Geriatr Med (in press) [SCI]
  • Chen LK (corresponding author), Lee WJ, Peng LN, Liu LK, Arai H, Akishita M; and Asia Working Group for Sarcopenia. Recent advances for sarcopenia research in Asia: report of the Asian Working Group for Sarcopenia. J Am Med Dir Assoc (accepted) [SCI]
  • Chen LK (corresponding author), Hwang AC, Liu LK, Wee WJ, Peng LN. Frailty is a complex geriatric syndrome with multiple functional needs: A comprehensive approach is needed. J Frailty Aging (accepted)
  • Lin CW, Wen YW, Chen LK (co-corresponding author), Hsiao FY. High-risk medications and unplanned hospitalizations: a case-time-control study. Sci Rep (in revision)
  • Chen LY, Liu LK, Lee WJ, Hwang AC, Lin MH, Peng LN, Chen LK (corresponding author). Association between serum IGF-1, bone mineral density, muscle mass and physical activities. Plos One (in revision) [SCI]
  • Hsu WH, Wen YW, Chen LK, Hsiao FY. A comparison of long-term anticholinergic burden derived from different risk scales with adverse clinical outcomes in the elderly: a longitudinal cohort study. J Am Med Dir Assoc (under review) [SCI]
  • Chen LK (corresponding author), Chen LY, Chou MY, Arai H, Chang WW, Djauzi S, Dong BR, Kojima T, Kwon KT, Leung EMF, Leong HN, Liang CK, Liu XH, Mathai D, Pan JY, Peng LN, Poblete E, Poi P, Redi S, Tantawichien T. Looking back to move forward: a twenty-year audit of herpes zoster in Asia-Pacific. BMC Infec Dis (under review) [SCI]
  • Chen LY, Hwang AC, Liu LK, Lin MH, Peng LN, Chen LK. Fatal rhinocerebral mucomycosis complicated with subarachnoid hemorrhage and late carotid and cerebral thrombosis. J Microbiol Immunol Infect (under review) [SCI]
  • Hsu CH, Tung HH, Chen LK, Yin WH, Wang TJ. Physical Activity as a Primary Health Quality Determinant Among Community-Dwelling Geriatric Women in Taiwan: Classification and Regression Tree Analysis. International Journal for Quality of Health Care (under review) [SCI]
  • Chang CC, Hsu CY, Chang TY, Huang PH, Liu LK, Chen LK, Chen JW, Lin SJ. Association between frailty and low-grade albuminuria: The Taiwan I-Lan Longitudinal Aging Study. Am J Med (under review)
  • Lee WJ, Chen LK, Peng LN, Chiou ST, Chou P. Personal mastery attenuates the adverse effect of frailty on declines in physical function of older people: a six-year population-based cohort study. Medicine (under review) [SCI]
  • Chang CC, Hsu CY, Huang PH, Liu LK, Chen LK (co-corresponding author), Chen JW, Lin SJ. Association between frailty and carotid intima media thickness and inflammatory marker in an elderly population. Geriatr Gerontol Int (under review) [SCI]
  • Lee WJ, Peng LN, Liang CK, Chou P, Chiou ST, Chen LK (corresponding author). Long sleep duration, independent of frailty and chronic inflammation, is associated with higher mortality: a nationwide population-based study. Geriatr Gerontol Int (under review) [SCI]
  • Lee WJ, Peng LN, Chou MY, Chiou ST, Chen LK (corresponding author). Relative muscle index is a simple indicator of cardiometabolic risk among middle-aged and older people: a nationwide population-based study in Taiwan. Plos One (under review) [SCI]
  • Chung CP, Chou KH, Chen WT, Liu LK, Lee WJ, Sheng WY, Chen LK, Lin CP, Wang PN. Strictly cerebral microbleeds are associated with deficits in global cognitive and visuospatial executive function. Stroke (under review) [SCI]
  • Huang TY, Liang CK, Shen HC, Chen HI, Liao MC, Chou MY, Lin YT, Lam HC, Tu MS, Chen LK (co-corresponding author). Dynapenia is a simple indicator for complex care needs among older men living in veterans care homes in Taiwan: a cross-sectional study using minimum data set. Plos One (under review) [SCI]
  • Lee WJ, Peng LN, Chiou ST, Chen LK (corresponding author). Physical measures improved prediction for cardiovascular and all-cause mortality: a nationwide population-based cohort study. J Am Coll Cardiol (under review) [SCI]
  • Chung CP, Chou KH, Chen WT, Liu LK, Lee WJ, Chen LK (co-corresponding author), Lin CP, Wang PN. The location of cerebral microbleeds determined their association with carotid intima media thickness: a community-based study. Cerebrovasc Dis (under review) [SCI]
  • Lin SY, Lee WJ, Chou MY, Peng LN, Chiou ST, Chen LK (corresponding author). Frailty index predicting all-cause mortality among middle-aged and older adults in Taiwan: a population-based cohort study. Plos One (under review) [SCI]
  • Tang TC, Hwang AC, Liu LK, Lee WJ, Lin MH, Peng LN, Chen LY, Wu YH, Huang CY, Hung CH, Wang CJ, Chen LK (corresponding author). FNIH-defined sarcopenia predicts adverse outcomes among community-dwelling older people in Taiwan: Results from I-Lan longitudinal aging study. J Am Med Dir Assoc (in submission) [SCI]
  • Hung CH, Chen LY, Peng LN, Hsiao FY, Chen LK (corresponding author). Recurrent falls and the risk factors among older men living in the veterans retirement communities: a cross-sectional study. J Nutr Health Aging (in preparation).
  • Wang CJ, Chen LY, Peng LN, Hsiao FY, Chen LK (corresponding author). Urinary incontinence and its association with frailty among men aged 80 years and older in Taiwan: a cross-sectional study. Neurourol Urodyn (in preparation)
  • Chen LY, Chen XJ, Yen J, Chen LK (co-corresponding author). Frailty is associated with long-term adverse outcomes among hospitalized older patients: a prospective cohort study in China. Plos One (in preparation)
  • Hsu H, Lin SW, Yang CL, Chen LK (corresponding author). The “3 Plus 1 Integrated Program” improved cardiovascular health and physical fitness for community-dwelling older adults in Taiwan. Eur Geriatr Med (in preparation).
  • Liu LK, Lee WJ, Chen LY, Hwang AC, Lin MH, Peng LN, Kuo CY, Chen LK (corresponding author), Liang KY. Are there subtypes of frailty? Latent class analysis from I-Lan longitudinal aging study. J Am Med Dir Assoc (in preparation)
  • Peng LN, Chen Y, Chen LK, Tung HH, Chu KH, Liang SY. Cognition and social-physiological factors associated with malnutrition in hospitalized older adults in Taiwan. J Nurs Res 2015;23:1-5 [SCI]
  • Lu WH, Wen YW, Chen LK, Hsiao FY. Changes of polypharmacy, potentially inappropriate medications and anticholinergic burden and associated clinical outcomes: a nationwide 10-year longitudinal study among people aged 65-74, 75-84 and 85+ years in Taiwan. CMAJ 2015;187:E30-7
  • Yao CA, Ho JC, Yang KC, Chen LK (co-corresponding author), Huang KC. The safety, tolerability and immunogenicity of ZOSATAVAXTM in healthy Taiwanese adults. Vaccine 2015;33:1515-7.
  • Hsiao FY, Peng LN, Wen YW, Liang CK, Wang PN, Chen LK (corresponding author). Care for older people with dementia and clinical effects of acute hospital admissions: a nationwide propensity score-matched cohort study. Plos One 2015;10:e0124973
  • Chen LY, Yang SP, Chen TL, Liao SY, Chen YY, Chan YJ, Chen LK, Wang FD. Clinical significance of time to positivity for yeast in candidemia. J Microbiol Immunol Infec (in press)
  • Peng LN, Chen YT, Liu LK, Lin MH, Chen WM, Chen LK (corresponding author). Clinical benefits of post-acute care for older patients with hip fractures in Taiwan: a prospective intervention cohort study. Geriatr Gerontol Int (in press) [SCI]
  • Huang WF, Chang LC, Kao YH, Wen YW, Hsiao FY, Tsai YW, Chen LK (corresponding author). Prolonged risk of subtrochanteric and diaphyseal femur fracture after discontinuing alendronate treatment: a nationwide nested case-control study in Taiwan. J Clin Gerontol Geriatr (in press) [SCI]
  • Chen LY, Liu LK, Hwang AC, Lin MH, Peng LN, Chen LK (corresponding author), Lan CF, Chang PL. Impact of malnutrition on physical, cognitive function and mortality among older men living in veteran homes by minimum data set: a prospective cohort study in Taiwan. J Nutr Health Aging (in press) [SCI]
  • Huang CC, Hsieh WJ, Lee PL, Peng LN, Liu LK, Lee WJ, Huang JK, Chen LK (co-corresponding author), Lin CP. Age-related changes in resting-state networks of a large sample size of healthy elderly. CNS Neurosci Ther (in press) [SCI]
  • Liang CK, Chou MY, Chu CL, Liao MJ, Lin YT, Chen LK (co-corresponding author). Developing a prediction model for postoperative delirium in association with long-term health outcomes among older patients receiving elective orthopedic surgery in Taiwan: A prospective cohort study. Rejuvenation Res (in press) [SCI]
  • Lee YT, Tsai YC, Chen LK (corresponding author). Evolutionary changes of artistic and neuropsychological performance of a Chinese painting master with Alzheimer’s dementia: first case in the world. Cortex (in press)
  • Liu ME, Chou MY, Liang CK, Ho CA, Lin YT, Lo YK, Peng LN, Chen LK. No adverse impact of depressive symptoms on the effectiveness of postacute care service: A multicenter male-predominant prospective cohort study. J Chin Med Assoc 2014;77:38-43 [SCI]
  • Arai H, Akishita M, Chen LK. Growing research on sarcopenia in Asia. Geriatr Gerontol Int 2014;14 Suppl 1:1-7. [SCI]
  • Meng P, Hu YX, Fan L, Zhang Y, Zhang MX, Sun J, Li M, Liu Y, Yang Y, Wang LH, Zhang Y, Gao W, Chen LK (corresponding author). Sarcopenia and sarcopenic obesity among men age 80 years and older in Beijing: prevalence and its association with functional performance. Geriatr Gerontol Int 2014;14 Suppl 1:29-35 [SCI]
  • Liu LK, Lee WJ, Chen LY, Hwang AC, Lin MH, Peng LN, Chen LK (corresponding author). Sarcopenia and its association with cardiometabolic and functional characteristics in Taiwan: Results from I-Lan longitudinal aging study. Geriatr Gerontol Int 2014;14 Suppl 1:36-45. [SCI]
  • Hsu YH, Liang CK, Chou MY, Liao MC, Lin YT, Chen LK, Lo YK. Association of psychomental conditions and sarcopenia among older men living in the veterans retirement community in southern Taiwan: a cross-sectional study. Geriatr Gerontol Int 2014;14 Suppl 1:102-8 [SCI]
  • Chen LK (corresponding author), Liu LK, Woo J, Assantachai P, Auyeung TW, Bahyan KS, Chou MY, Chen LY, Hsu PS, Krairit O, Lee JSW, Lee WJ, Lee YH, Liang CK, Limpawattana P, Lin CL, Peng LN, Satake S, Suzuki T, Won CW, Wu CH, Wu SN, Zhang TM, Zeng P, Akishita M, Arai H. Sarcopenia in Asia: consensus report of the Asian Working Group of Sarcopenia. J Am Med Dir Assoc 2014;15:95-101 [SCI]
  • Lee WJ, Chen LK, Tang GJ, Lan TY. The impact of influenza vaccination on hospitalizations and mortality among frail elderly persons. J Am Med Dir Assoc 2014;15:256-60 [SCI]
  • Lee WJ, Chou MY, Peng LN, Liang CK, Liu CL, Chen LK (corresponding author), Wu YH and VAIC Study Group. Predicting clinical instability of older patients in post-aucte units in Taiwan: a nationwide cohort study. Geriatr Gerontol Int 2014;14:267-72 [SCI]
  • Chen RC, Liu CL, Lin MH, Peng LN, Chen LY, Liu LK, Chen LK (corresponding author). Non-pharmacological treatment reducing not only behavioral symptoms but also psychiatric symptoms of demented older adults in Taiwan: a prospective cohort study. Geriatr Gerontol Int 2014;14:440-6. [SCI]
  • Chang CJ, Chen LY, Peng LN, Lin MH, Chen LK (co-corresponding author). Lymphpenia and poor performance status as major predictors for infections among residents in long-term care facilities: a prospective cohort study. Arch Gerontol Geriatr 2014;58:440-5 [SCI]
  • Yeh KP, Chen LY, Lin MH, Liu LK, Liu CL, Peng LN, Chen LK (corresponding author). Physical dependence and early functional decline associated with higher mortality risk among older residents in Veteran Homes. J Clin Gerontol Geriatr 2014;5:13-17
  • Peng LN, Lin MH, Liu LK, Chen LY, Chu KH, Lin KC, Tung HH, Won CW, Chen LK (corresponding author). Nutritional status plays the mediating role of the functional status and comorbidity among older patients admitted to the geriatric evaluation and management unit: a Tobit model application. Eur Geriatr Med 2014;5:87-92 [SCI]
  • Chen YC, Fan JS, Chen MH, Hsu TF, Huang HH, Cheng KW, Yen DH, Huang CI, Chen LK, Yang CC. Risk factors associated with adverse drug events among older adults in emergency department. Eur J Intern Med 2014;25:49-55. [SCI]
  • Hwang AC, Peng LN, Wen YW, Tsai YW, Chang LC, Chiou ST, Chen LK (corresponding author). Predicting mortality by static and dynamic measurements of allostatic load: a 10-year population-based cohort study in Taiwan. J Am Med Dir Assoc 2014;15:40-6 [SCI]
  • Hsiao FY, Peng LN, Lin MH, Chen LK (corresponding author). Dose-responsive effect of psychotropic drug use and subsequent dementia: a nationawide propensity matched case-control study in Taiwan. J Am Med Dir Assoc 2014;15:509-13 [SCI]
  • Liu LK, Chen LY, Yeh KP, Lin MH, Peng LN, Chen LK. Sarcopenia but not sarcopenic obesity predicts mortality for older men: a 3-year prospective cohort study. J Clin Gerontol Geriatr 2014;5:42-46.
  • Tung HH, Lu TM, Chen LK, Liang SY, Wu SF, Chu KH. Health literacy impact on elderly patients with heart failure in Taiwan. J Clin Gerontol Geriatr 2014;5:72-76.
  • Chang LC, Loh EW, Tsai YW, Chiou ST, Chen LK (corresponding author). Clinical benefits of smoking cessation in reducing all-cause and disease-specific mortality among older people in Taiwan: a 10-year nationwide retrospective cohort study. Eur Geriatr Med 2014;5:149-54 [SCI]
  • Liang CK, Chou MY, Liao MC, Lin YT, Lo YK, Chen LK (co-corresponding author). Predicting falls of men aged 80 years and older in Taiwan by gait speed: a prospective cohort study. Eur Geriatr Med 2014;5:298-302 [SCI]
  • Liu LK, Liu CL, Peng LN, Chen LY, Su CT, Lin MH, Chen LK (corresponding author). Undiagnosed diabetes mellitus among residents in Taiwanese long-term care facilities: comparisons of using fasting, postprandial plasma glucose and hemoglobin A1c. J Clin Gerontol Geriatr 2014;5:68-71 [SCI]
  • Cruz-Jentoft AJ, Landi F, Schneider S, Zuniga C, Arai H, Boirie Y, Chen LK, Fielding RA, Harris T, Martin FC, Michel JP, Sieber C, Stout JR, Studenski S, Vellas B, Woo J, Zamboni M, Cederholm T. Prevalence of and interventions for sarcopenia in ageing adults – a systemic review. Report of the International Sarcopenia Initiative (EWGSOP and IWGS). Age Ageing 2014;43:748-59 [SCI]
  • Liang CK, Chu CL, Chou MY, Lin YT, Lo YK, Lu T, Hsu CJ, Chen LK (co-corresponding author). Synergistic effect of delirium and cognitive impairment on adverse functional outcomes of older patients receiving orthopedic surgery: a prospective cohort study. PloS One 2014;9:e110339 [SCI]
  • Chen LY, Liu LK, Peng LN, Lin MH, Chen LK (corresponding author), Lan CF, Chang PL. Identifying residents at greater risk for cognitive decline by minimum data set in long-term care settings. J Clin Gerontol Geriatr 2014;4:122-6.
  • Tsai YW, Hsiao FY, Wen YW, Chang LC, Huang WF, Chen LK (corresponding author). Clinical outcomes of vertebroplasty or kyphoplasty for patients with vertebral compression fractures: a nationwide cohort study. J Am Med Dir Assoc 2013;14:41-7 [SCI]
  • Liu LK, Peng LN, Chen LY, Liu CL, Lin MH, Chen LK (corresponding author). Timed Up-and-Go test: a potential indicator for successful aging of oldest old men. J Aging Res Clin Pract 2013;2:152-6.
  • Chen LY, Kuo SC, Wu HS, Yang SP, Chan YJ, Chen LK, Wang FD. Associated clinical characteristics of patients with candidemia among different Candida species. J Microbiol Immunol Infect (in press) [SCI]
  • Chen YC, Liu L, Peng LN, Lin MH, Chen LK (corresponding author), Chen TJ, Hwang SJ. Cataract surgery utilization after acute stroke: a nationwide cohort study. J Clin Gerontol Geriatr 2013;4:7-11
  • Chiou SH, Jiang BH, Chou SJ, Tsai PH, Chang WC, Yu YL, Chen LK, Chen LH, Chien Y, Chiou GY. Poly(ADP-ribose) polymerase 1 regulates nuclear reprogramming and promotes iPSC generation without c-myc. J Exp Med 2013;210:85-98 [SCI]
  • Yeh YC, Liu CL, Peng LN, Lin MH, Chen LK (corresponding author). Efficacy and safety of reducing anticholinergic burden among demented older people in the dementia care unit: a prospective cohort study. Geriatr Gerontol Int 2013;13:694-700 [SCI]
  • Tung HH, Wei J, Chen LK, Tsai JC, Lin KC, Lin YP. Development of self-care simulation education in older patients with heart failure. J Clin Gerontol Geriatr 2013;4:1-3.
  • Kao YH, Chang LC, Huang WF, Tsai YW, Chen LK (corresponding author). Impact of rotating living with adult children on health of older Taiwanese: a national survey. J Am Med Dir Assoc 2013;14:331-5 [SCI]
  • Lee WJ, Liu LK, Peng LN, Lin MH, Chen LK (corresponding author), and ILAS research group. Sarcopenia in Taiwan: comparisons between IWGS and EWGSOP criteria. J Am Med Dic Assoc 2013;14:528.e1-7 [SCI]
  • Liu CL, Lin MH, Peng LN, Chen LK (corresponding author), Su CT, Liu LK, Chen LY. Late-life metabolic syndrome prevents cognitive decline among older men aged 75 years and over in Taiwan. J Nutr Health Aging 2013;17:523-6 [SCI]
  • How CK, Chien Y, Yang KY, Shih HC, Juan CC, Yang YP, Chiou GY, Chen LK, Wang CY, Lee CH, Hsu HS, Chiou SH. Induced pluripotent stem cells mediate the release of interferon gamma-induced protein 10 (IP-10) and alleviate bleomycin-induced lung inflammation and fibrosis. Shock 2013;39:261-70. [SCI]
  • Chen LY, Liu LK, Liu CL, Peng LN, Lin MH, Chen LK (co-corresponding author), Lan CF. Predicting functional decline of older men living in the Veteran Homes in Taiwan: Implications for disability prevention in long-term care settings. J Am Med Dir Assoc 2013;14:309.e9-13 [SCI]
  • Berrut G, Andrieu S, Araujo de Carvalho I, Baeyens JP, Bergman H, Cassim B, Cerreta F, Cecasi M, Cha HB, Chen LK, et al. Promoting Access to Innovation for Frail Old Persons. IAGG, WHO, and SFGG Workshop – Athens January 20-21, 2012 Tool (GFST). J Nutr Health Aging 2013;17:688-93.
  • Liu LK, Lee WJ, Liu CL, Peng LN, Chen LY, Lin MH, Chen LK (corresponding author). Association of age-related skeletal muscle loss and physical performance in Taiwan: Implications to diagnostic strategy of sarcopenia in Asia. Geriatr Gerontol Int 2013;13:964-71. [SCI]
  • Tung HH, Cheng Y, Shih CC, Chen LK, Lee JY, Wang TJ. Quality of life among patients with abdominal aortic aneurysm undergoing endografting in Taiwan. Eur J Cardiovasc Nurs 2013;13:369-77[SCI]
  • Chen LY, Peng LN, Liu LK, Lin MH, Chen LK (corresponding author), Chang PL, Lan CF. Body mass index, health status, and mortality of older Taiwanese men: overweight good, underweight bad, obesity neutral. J Am Geriatr Soc 2013;61:2233-4. [SCI]
  • Hwang AC, Liu LK, Lee WJ, Liu CL, Chen LY, Lin MH, Peng LN, Won CW, Chen LK (corresponding author). Association of androgen with skeletal muscle mass and muscle function among men and women age 50 years and older in Taiwan: Results from I-Lan longitudinal aging study. Rejuvenation Res 2013;16:453-9 [SCI]
  • Chen LY, Kuo SC, Wu HS, Yang SP, Chan YJ, Chen LK, Wang FD. Associated clinical characteristics of patients with candidemia among different Candida species. J Microbiol Immunol Infec 2013;46:463-8.
  • Chen LK (corresponding author), Inoue H, Won CW, Lin CH, Lin KF, Tsay SF, Lin PF, Li SH. Challenges of urban aging in Taiwan: Summary of urban aging forum. J Clin Gerontol Geriatr 2013;4:97-101.
─ Aging and Technology Research ─
  • Lin HW, Wang YJ, Jing LF, Chang P. (2014, Jun). Mockup design of personal health diary app for patients with chronic kidney disease. Studies in Health Technology and Informatics, 201:124-132.
  • Weng WK, Chang P. (2014, Jun).Developing mobile support system for dynamic integrated community-based screening. Studies in Health Technology and Informatics, 201:257-263.
  • Lee YL, Chien TF, Kuo MC, *Chang P. (2014, Jun). The relationship of learning motivation, achievements and satisfaction for nurses learning simple Excel VBA information systems programming. Studies in Health Technology and Informatics, 201:364-370.
  • Kuo MC, *Chang P. (2014, Jun).A total design and implementation of an intelligent mobile chemotherapy medication administration. Studies in Health Technology and Informatics, 201:441-6
  • Feng RC, Tseng KJ, Yan HF, Huang HY, *Chang P. (2013, Dec). A Preliminary Study on the Use of Clinical Care Classification in Nursing Documentation Data Sets. Computer Methods and Programs in Biomedicine, 112(3):713-9. doi: 10.1016/j.cmpb.2013.07.019. Epub 2013 Aug 7.
  • Huang YC, Chang KY, Lin SP, Chen K, Chan KH, *Chang P. (2013, Aug). Development of a daily mortality probability prediction model from Intensive Care Unit patients using a discrete-time event history analysis. Computer Methods and Programs in Biomedicine, 111(2):280-9. doi: 10.1016/j.cmpb.2013.03.018. Epub 2013 May 17.
  • Kao W-F, Huang J-H, Kuo TBJ, Chang P-L, Chang W-C, et al. (2013, Jun). Real-Time Electrocardiogram Transmission from Mount Everest during Continued Ascent. PLOS One, DOI: 10.1371/journal.pone.0066579.
  • Chen LY, Liu LK, Liu CL, Peng LN, Lin MH, *Chen LK, Lan CF, Chang P. Predicting Functional Decline of Older Men Living in Veteran Homes by Minimum Data Set: Implications for Disability Prevention Programs in Long Term Care Settings. JAMDA 14 (2013) 309.e9-309.e13.
  • Hou IC, *Chang P, Chan HY, Dykes PC. A Modified Delphi Translation Strategy and Challenges of International Classification for Nursing Practice (ICNP®), Int J Med Inform. 2012 Sep 11. pii: S1386-5056(12)00153-0. doi: 10.1016/j.ijmedinf.2012.08.002.
  • Long AJ, *Chang P. The effect of using the Health Smart Card vs. CPOE reminder system on the prescribing practices of non-obstetric physicians during outpatient visits for pregnant women in Taiwan, Int J Med Inform. 2012 Sep;81(9):605-11. doi: 10.1016/j.ijmedinf.2012.04.009. Epub 2012 Jun 15.
  • Kuo MC, *Chang P, Feng RC, Westra B, Ball M. From Passion to Excellence: National NI Movement in Taiwan. CIN: Computers, Informatics, Nursing. 2012;30(5):234-6.
  • Huang F, *Chang P. The feasibility of building a self-report component for the Taiwan version of MDS-NH. The Journal of Taiwan Association for Medical Informatics. 2011;20(4):39-51.